Marcador D8-17: implicações para a neuropsiquiatria
نویسندگان
چکیده
منابع مشابه
D8/17 Monoclonal Antibody: An Unclear Neuropsychiatric Marker
OBJECTIVE It has been hypothesized that monoclonal antibody D8/17 identifies a B lymphocyte antigen with expanded expression in patients with rheumatic fever, childhood onset obsessive-compulsive disorder (OCD), Tourette syndrome (TS) or prepubertal anorexia nervosa (AN). Our purpose was to replicate these studies in a Spanish population and to determine whether D8/17 identifies a subgroup of t...
متن کاملCell Alloantigen D8/17 in Indian Patients With Rheumatic Heart Disease
D8/17, a B cell alloantigen, and its occurrence with DR/DQ antigens was examined in 54 patients with rheumatic heart disease and matched North Indian controls. Thirty-four patients (62.9%) carried D8/17 as compared with a frequency of 12.5% in controls (X2 by Yates', 18.75; p<0.0001). A marginally increased frequency ofhuman leukocyte antigen (HLA)-DR3 (44.2% vs. 28.8%) and a significantly redu...
متن کاملD8/17 and CD19 expression on lymphocytes of patients with acute rheumatic fever and Tourette's disorder.
D8/17, an alloantigen found on B lymphocytes, has been reported to be elevated in patients susceptible to rheumatic fever and may be associated with autoimmune types of neuropsychiatric disorders. The pediatric-autoimmune-neuropsychiatric-disorders-associated-with-streptococci model is a putative model of pathogenesis for a group of children whose symptoms of obsessive-compulsive disorder and T...
متن کاملPresence of a D8/17 B lymphocyte marker and HLA-DR subgroups in patients with rheumatic heart disease.
OBJECTIVE The aim of our study was to investigate the association of HLA antigens and a non-HLA protein D8/17 with rheumatic heart disease and its pattern of cardiac involvement. METHODS This cross- sectional observational study included 35 children and 12 adult patients who have rheumatic heart disease and 35 healthy children and 12 healthy adult controls. After physical examination, all pat...
متن کاملThe D0−D8 system revisited
We address a few subtle issues regarding the interacting D0-D8 system. There are two existing interpretations for the counter-intuitive non-vanishing attractive cylinder-diagram R-R potential. We improve them each by properly dealing with the divergence of potential in the R-R as well as the NS-NS sector, which has been ignored so far. We further test them by considering the D8 to carry a flux,...
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ژورنال
عنوان ژورنال: Arquivos de Neuro-Psiquiatria
سال: 2000
ISSN: 0004-282X
DOI: 10.1590/s0004-282x2000000200028